Curriculum vitae

Education

Research Experience

Peer-Reviewed Research Articles

1. Brain endothelial cells orchestrate a neuroprotective antiviral state in the central nervous system in response to peripheral viral pattern sensing↗ (opens in a new tab).
   Lewy T, Sierra MA, Pourshadi N, Hoffmann HH, Dinnon KH, Gola A, Wang W, Chen HA, Quirk C, Zhang H, Doyle MP, Mason CE, Diehl GE, Hohl TM, Fuchs E, MacDonald MR, Wu Z, Crowe JE, Rice CM, Lercher A.
   Immunity 2026;59(7):1825–1842.e11. doi:10.1016/j.immuni.2026.06.009
2. An immunocompetent murine model of virus-elicited liver fibrosis and hepatocellular carcinoma↗ (opens in a new tab).
   Batista MN, Bordignon J, Pamplona Mosimann AL, Bobrowski T, Chen HA, Tobin-Xet G, Barrall EA, Prokhnevska N, Vaidya AB, Lewy T, Dinnon KH, Seifert LL, Zeck B, Quirk C, Ho YJ, Filliol A, Wolfisberg R, Jiang C, Cogliati B, Chiriboga L, Theise N, MacDonald MR, Kamphorst AO, Scheel TK, Sheahan TP, Billerbeck E, Lowe SW, Rosenberg BR, Rice CM.
   Journal of Hepatology 2026. doi:10.1016/j.jhep.2026.02.020
3. Antiviral innate immune memory in alveolar macrophages following SARS-CoV-2 infection ameliorates secondary influenza A virus disease↗ (opens in a new tab).
   Lercher A, Cheong JG, Bale MJ, Jiang C, Hoffmann HH, Ashbrook AW, Lewy T, Yin YS, Quirk C, DeGrace EJ, Chiriboga L, Rosenberg BR, Josefowicz SZ, Rice CM.
   Immunity 2024;57(11):2530–2546.e13. doi:10.1016/j.immuni.2024.08.018
4. A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist↗ (opens in a new tab).
   Le Pen J, Paniccia G, Bauer M, Hoffmann HH, Kinast V, Moncada-Velez M, Pinharanda A, Ricardo-Lax I, Stenzel AF, Rosado-Olivieri EA, Ashbrook AW, Dinnon KH, Doyle WC, Freije CA, Hong SH, Lee D, Lewy T, Luna JM, Peace A, Schmidt C, Schneider WM, Winkler R, Larson C, McGinn T, Menezes MR, Ramos-Espiritu L, Banerjee P, Poirier JT, Sánchez-Rivera FJ, Zhang Q, Casanova JL, Carroll TS, Glickman FJ, Michailidis E, Razooky B, MacDonald MR, Rice CM.
   PLoS Biology 2024;22(9). doi:10.1371/journal.pbio.3002767
5. PERK-mediated unfolded protein response signaling restricts replication of the tick-borne flavivirus Langat virus↗ (opens in a new tab).
   Lewy TG, Offerdahl DK, Grabowski JM, Kellman E, Mlera L, Chiramel A, Bloom ME.
   Viruses 2020;12(3):328. doi:10.3390/v12030328
6. Oral microbiome in HIV-infected women: shifts in the abundance of pathogenic and beneficial bacteria are associated with aging, HIV load, CD4 count, and antiretroviral therapy↗ (opens in a new tab).
   Lewy T, Hong BY, Weiser B, Burger H, Tremain A, Weinstock G, Anastos K, George MD.
   AIDS Research and Human Retroviruses 2019;35(3):276–286. doi:10.1089/AID.2017.0200

Reviews

1. Spatial omics technologies at multimodal and single cell/subcellular level↗ (opens in a new tab).
   Park J, Kim J, Lewy T, Rice CM, Elemento O, Rendeiro AF, Mason CE.
   Genome Biology 2022;23(1):256. doi:10.1186/s13059-022-02824-6
2. BiP: master regulator of the unfolded protein response and crucial factor in flavivirus biology↗ (opens in a new tab).
   Lewy TG, Grabowski JM, Bloom ME.
   Yale Journal of Biology and Medicine 2017;90(2):291–300. PMID 28656015

Writing for General Audiences

1. Misuse of antibiotics leads to antibiotic resistant bacteria↗ (opens in a new tab).
   Lewy TG.
   Prized Writing, University of California, Davis. 2014;25:113–119

Selected Presentations

Teaching & Mentoring

Honors & Distinctions

References available on request.

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